The Leader has obtained a sample of Bruce Banner's gamma irradiated blood and used it to cause a "green flu" that is bringing down the inhabitants of New York City. With Spider-Man and the Avengers after him, Hulk uncovers the fact that the Leader has infected the city's water supply and the disaster is averted.
Doc Samson figures out a way to touch the untouchable Unus.
Additional information on contents of comic provided by Terry Vraspir (May 28, 2004).
- - Classified ads. Appears after page 3 of the main story.
- - Appears after page 11 of the main story.
- - Promo ad for subscription to current Marvel titles. Appears after page 14 of the main story.
- - Appears after page 20 of the main story.
- - Appears after page 26 of the main story.
- - Appears after page 29 of the main story.
- - Includes Items, The Hype Box and Mighty Marvel Checklist.
- Unus Unchained - Editor, Al Milgrom, explains that this is the first pencil job Frank Miller did for Marvel and is presented here for the first time.
- - Appears after page 3 of the Doc Samson story.
- - Classified ads.
- Power! - Promo for Marvel Comics.
- Bring the Battle Home! - Advertisement for Star Wars: The Empire Strikes Back video game cartridge. Appears on the back cover.